The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery

Hans G. Beger, Andrew L. Warshaw, Ralph H. Hruban, Markus W. Buchler, Markus M. Lerch, John P. Neoptolemos, Tooru Shimosegawa, David C. Whitcomb

John Wiley & Sons, 23 апр. 2018 г. - Всего страниц: 1216

This brand new updated edition of the most comprehensive reference book on pancreatic disease details the very latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known disorders. Included for the first time, are two brand new sections on the key areas of Autoimmune Pancreatitis and Benign Cystic Neoplasms. In addition, this edition is filled with over 500 high-quality illustrations, line drawings, and radiographs that provide a step-by-step approach to all endoscopic techniques and surgical procedures. Each of these images can be downloaded via an online image bank for use in scientific presentations.

Every existing chapter in The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition has been thoroughly revised and updated to include the many changes in clinical practice since publication of the current edition. The book includes new guidelines for non-surgical and surgical treatment; new molecular biologic pathways to support clinical decision making in targeted treatment of pancreatic cancer; new minimally invasive surgical approaches for pancreatic diseases; and the latest knowledge of neuroendocrine tumors and periampullary tumors.

The most encyclopedic book on the pancreas—providing outstanding and clear guidance for the practicing clinician
Covers every known pancreatic disorder in detail including its anatomy, physiology, pathology, pathophysiology, diagnosis, and management
Completely updated with brand new chapters
Over 500 downloadable illustrations
An editor and author team of high international repute who present global best-practice

The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery, 3rd Edition is an important book for gastroenterologists and gastrointestinal surgeons worldwide.

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Избранные страницы

Содержание

About the Companion Website xlii	42

Anatomy Histology and Fine Structure of the Pancreas 10	10

Congenital and Inherited Anomalies of the Pancreas 24	24

Physiology and Pathophysiology of Pancreatic Functions 41	41

Physiology of Duct Cell Secretion	56

Pathophysiology of Experimental Pancreatitis	63

Physiology and Pathophysiology of Function of Sphincter of Oddi	75

Neurohormonal and Hormonal Control of Pancreatic Secretion	84

University of Verona	560

Benign Cystic Neoplasms of the Pancreas	565

Histologic Classification and Staging of Cystic Neoplasms	573

Clinical Presentation of Cystic Neoplasms	589

Cytologic Evaluation of Cystic Neoplasms	603

Surveillance or Surgical Treatment in Asymptomatic Cystic Neoplasms	618

The Indications For and Limitations of Tumor Enucleation	632

Laparoscopic Approach	649

Regulation of Pancreatic Protein Synthesis and Growth	95

The Role of Stellate Cells	106

The Role of Macrophages	117

Acute Pancreatitis	133

Epidemiology and Etiology of Acute Biliary Pancreatitis	146

The Role of the Intestine and Mesenteric Lymph in the Development of Systemic Inflammation and MODS	166

Histopathology of Acute Pancreatitis	193

Acute Pancreatitis Associated With Congenital Anomalies	213

Acute Pancreatitis Associated With Metabolic Disorders Infectious Diseases or Drugs	230

Clinical Course and Medical Treatment of Acute Pancreatitis	251

Indications and Limitations	265

Thomas E Clancy MD	271

Albers	277

Minimally Invasive Debridement and Lavage of Necrotizing Pancreatitis	283

Endoscopic Treatment of Biliary Acute Pancreatitis	296

Management of Fluid Collection in Acute Pancreatitis	311

Chronic Pancreatitis	331

Pain Mechanisms in Chronic Pancreatitis	349

Chronic Pancreatitis with Inflammatory Mass of the Pancreatic Head	365

Epidemiology and Pathophysiology of Tropical Chronic Pancreatitis	384

Clinical and Laboratory Diagnosis of Chronic Pancreatitis	397

Risk Factors in Cancer	417

University of Miami Sinead N Duggan RD	429

Antioxidants	435

Indications and Goals of Surgical Treatment	449

Major Pancreatic Resection	467

Management of Diabetes and LongTerm Outcome of Chronic Pancreatitis	488

Autoimmune Pancreatitis	503

Histology of Autoimmune Pancreatitis	516

Clinical Manifestations of Type 2 Autoimmune Pancreatitis	534

Imaging Diagnosis of Autoimmune Pancreatitis	550

Pancreatic Cancer	665

Molecular Understanding of Development of Ductal Pancreatic Cancer	679

Pathology of Exocrine Pancreatic Tumors	693

Clinical History and Risk Factors of Pancreatic Cancer	717

CT MRI	733

The Role of PET in Diagnosis of Pancreatic Cancer and Cancer Recurrence	755

Clinical Assessment and Staging of Advanced Pancreatic Cancer	770

Pancreaticoduodenectomy for Pancreatic Cancer Short and LongTerm Outcomes After KauschWhipple	783

Indications and Limitations	797

Laparoscopic and Robotic Resection for Pancreatic Cancer	804

Benefits and Limitations	823

Medical Treatment of Pancreatic Cancer	842

Immunotherapy for Pancreatic Cancer	856

Survival Benefit and Side Effects of Treatment	872

Role of Radio and Proton Beam Therapy for Pancreatic Cancer	886

LongTerm Outcome After Treatment of Pancreatic Cancer	906

Neuroendocrine Tumors of the Pancreas	919

Pathology of Neuroendocrine Neoplasms	930

Clinical Manifestation of Endocrine Tumors of the Pancreas	947

Pancreatic Neuroendocrine Tumors in Multiple Neoplasia Syndromes	961

Interventional Radiology in the Treatment of Pancreatic Neuroendocrine Tumors	979

Major Oncologic Resection	994

Evidence of Medical and Surgical Treatment of Gastrinoma	1009

LongTerm Outcome After Treatment of Neuroendocrine Tumors of the Pancreas	1029

Clinical Presentation and Diagnostic Strategies	1037

Diagnosis and Management	1058

Surgical Treatment of Adenoma and Cancer of Papilla of Vater	1074

Adjuvant and Palliative Chemotherapy of Periampullary Cancers	1089

Transplantation of the Pancreas	1107

Transplantation of the Pancreas	1121

Авторские права

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The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery
Hans G. Beger,Andrew L. Warshaw,Ralph H. Hruban,Markus W. Buchler,Markus M. Lerch,John P. Neoptolemos,Tooru Shimosegawa,David C. Whitcomb
Ограниченный просмотр - 2018

Часто встречающиеся слова и выражения

acinar cells activation acute pancreatitis alcohol appears approach associated autoimmune pancreatitis Beger bile biliary Ca2+ cause changes chronic pancreatitis classification Clin clinical common compared complications cyst cystic cystic neoplasms cytoplasm Department diabetes diagnosis disease drainage ductal early effect endoscopic enzyme et al exocrine expression factors failure fibrosis Figure findings fistula fluid function Gastroenterol Gastroenterology gene genetic glucose head human imaging important increased indicated infected inflammatory initial injury International intervention invasive involvement IPMN John lead lesions levels long‐term major mechanisms Medicine mortality mucinous mutations necrosis necrotizing observed occur organ outcomes pain pancreatic cancer pancreatic duct patients Physiol present procedure protein pseudocysts rats recent receptor recurrent regulation release reported resection response risk role secretion severe showed stimulation suggest Surg Surgery surgical syndrome therapy tion tissue treatment trial tumor University

Об авторе (2018)

The Editors
HANS G. BEGER, MD, FACS(Hon), JSS(Hon), CSS(Hon), Founding Editor, Professor Emeritus of Surgery, c/o University of Ulm, Ulm, Germany

ANDREW L. WARSHAW, MD, FACS, FRCSEd(Hon), W. Gerald Austen Distinguished Professor of Surgery, Harvard Medical School, Surgeon-in-Chief Emeritus, Massachusetts General Hospital, Boston, MA, USA

RALPH H. HRUBAN, MD, Baxley Professor and Director, The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

MARKUS W. BÜCHLER, MD, Professor of Surgery and Chair, Department of Surgery, University of Heidelberg, Heidelberg, Germany

MARKUS M. LERCH, MD, FRCP, Professor and Chair, Department of Medicine A, University Medicine Greifswald, Greifswald, Germany

JOHN P. NEOPTOLEMOS, MA, MB, BCHIR, MD, FRCS, FMEDSCI, Professor of Surgery, Department of Surgery, University of Heidelberg, Heidelberg, Germany

TOORU SHIMOSEGAWA, MD, PhD, Professor, Department of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan

DAVID C. WHITCOMB, MD, PhD, Professor of Medicine, Cell Biology & Physiology, and Human Genetics, Director, UPMC Precision Medicine Service, University of Pittsburgh and UPMC, Pittsburgh, PA, USA

Библиографические данные

Название	The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery
Редакторы	Hans G. Beger, Andrew L. Warshaw, Ralph H. Hruban, Markus W. Buchler, Markus M. Lerch, John P. Neoptolemos, Tooru Shimosegawa, David C. Whitcomb
Издание:	3
Издатель	John Wiley & Sons, 2018
ISBN	1119188393, 9781119188391
Количество страниц	Всего страниц: 1216

Экспорт цитаты	BiBTeX EndNote RefMan

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