The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

Dan Purich earned his Ph.D. for ground-breaking work on brain hexokinase, adenine nucleotide control, and multisubstrate inhibitors under Herbert Fromm at Iowa State University. After investigating the glutamine synthetase adenylylation cascade as an NIH Staff Fellow under Earl Stadtman, he joined the Chemistry Department at UC Santa Barbara. Awarded a Sloan Fellowship in Chemistry and NIH Research Career Development Award, Purich rose to full professor before moving to the University of Florida College of Medicine to become Chair of Biochemistry & Molecular Biology. He served on the Journal of Biological Chemistry, Archives of Biochemistry & Biophysics, and Biophysical Chemistry editorial boards. He also edited the six-volume Enzyme Kinetics & Mechanism sub-series of Methods in Enzymology and wrote The Handbook of Biochemical Kinetics (2000), The Enzyme Reference (2002), and Enzyme Kinetics: Catalysis & Control (2010). Author of over 170 peer-reviewed papers, chapters and reviews on enzyme action and cytoskeleton self-assembly, Purich discovered the actoclampins, the (+)-end-tracking motors that power actin-based motility by harnessing the Gibbs energy of on-filament ATP hydrolysis, while catalyzing monomer insertion. For fun, he travels and writes mystery novels.