The Essence of Analgesia and Analgesics

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Raymond S. Sinatra, Jonathan S. Jahr, J. Michael Watkins-Pitchford
Cambridge University Press, 14 окт. 2010 г.
The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.
 

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Chapter 1 Introduction
1
Section 1 Pain Definitions
3
Section 2 Oral and Parenteral Opioid Analgesics
73
Section 3 Neuraxial Opioid Analgesics
181
Section 4 NSAIDs
211
Section 5 Local Anesthetics
266
Section 6 AnticonvulsantType Analgesics
291
Section 7 NMDA Antagonists
310
Section 8 AlphaAdrenergic Analgesics
327
Section 9 Antidepressants
337
Section 10 Muscle Relaxants
360
Section 11 Adjuvant Analgesics and Antiemetics
383
Section 12 New and Emerging Analgesics
424
Index
515
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Raymond S. Sinatra is Professor of Anesthesiology and Pain Management, Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut, USA.

Jonathan S. Jahr is Professor of Clinical Anesthesiology at the David Geffen School of Medicine, University of California, Los Angeles.

J. Michael Watkins-Pitchford is Assistant Professor of Anesthesiology and Pain Management, Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut, USA.

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