Chemical Warfare Agents: Chemistry, Pharmacology, Toxicology, and Therapeutics, Second Edition

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Brian J. Lukey, James A. Romano Jr., James A. Romano, Harry Salem, Brian J Lukey
CRC Press, 17 дек. 2007 г. - Всего страниц: 752
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The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.

Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, Second Edition explores the latest methods and products for preventing, diagnosing, and treating the acute and chronic effects of toxic CWA exposure. This edition citesthe key developments in chemical defense research since 2001, including new epidemiological or clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus in the U.S. addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment.

Leading researchers explain how these breakthroughs help researchers determine physiologically relevant detection thresholds and develop more effective countermeasures and national response procedures. Chemical Warfare Agents provides first responders and emergency medical teams with the most up-to-date information they need to prepare for and handle natural disasters, chemical spills, terrorism, and warfare situations—quickly and effectively.

 

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Chapter 1 Brief History and Use of Chemical Warfare Agents in Warfare and Terrorism
1
Chapter 2 Chemistry of Chemical Warfare Agents
21
Chapter 3 Chemical Warfare Agent Threat to Drinking Water
51
Chapter 4 Health Effects of LowLevel Exposure to Nerve Agents
71
Chapter 5 Toxicokinetics of Nerve Agents
97
Chapter 6 Application of Genomic Proteomic and Metabolomic Technologies to the Development of Countermeasures against Chemical Warfare Ag...
123
Chapter 7 Novel Approaches to Medical Protection against Chemical Warfare Nerve Agents
145
Progress in Development of a New Mode of Protection against Organophosphorus Exposure
175
Chapter 15 Chemicals Used for Riot Control and Personal Protection
343
Chapter 16 Mechanism of Action of Botulinum Neurotoxin and Overview of Medical Countermeasures for Intoxication
389
Review and Perspective
423
Applications Toxicology Clinical Considerations and Medical Management
469
Chapter 19 Clinical Detection of Exposure to Chemical Warfare Agents
501
Practical and Theoretical Considerations
549
Chapter 21 Chemical Warfare Agent Decontamination from Skin
611
An Assessment of Psychological Impact
627

Chapter 9 Butyrylcholinesterase and Its Synthetic CTerminal Peptide Confer In Vitro Suppression of Amyloid Fibril Formation
203
Connection to Alzheimers Disease and Dementia
219
Chapter 11 Inhalation Toxicology of Nerve Agents
233
Chapter 12 Vesicants and Oxidative Stress
247
Chapter 13 Health Effects of Exposure to Vesicant Agents
293
Toxicology Clinical Presentation and Medical Management
313
Domestic Preparedness First Response and Public Health Considerations
653
Chapter 24 Emergency Medical Response to a Chemical Terrorist Attack
675
Index
713
Back cover
725
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