The Renal Drug Handbook: The Ultimate Prescribing Guide for Renal Practitioners, 5th Edition
This invaluable guide, endorsed by the UKMi and reflecting the extensive experience of the UK Renal Pharmacy Group, features drug monographs guiding physicians in how to prescribe, prepare, and administer drugs to patients with different levels of kidney function and when undergoing renal replacement therapy. It has been fully updated for this fifth edition to include up to 100 additional drugs, while maintaining the clear structure and format that is easy to use and simple to follow in the busy clinical setting. It continues to offer support and guidance to health care professionals enabling them to prescribe medications to their renal patients appropriately and safely.
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Administration Reconstitution amphotericin Anticoagulants Antipsychotics APD/CAPD Not dialysed avoid concomitant carbamazepine caution CAV/VVHD Not dialysed CAV/VVHD Unknown dialysability CAV/VVHD Unlikely Ciclosporin clozapine concentration possibly increased daily Pharmacokinetics Molecular distribution L/kg Dose in normal Dose in patients Dose in renal drug interactions Potentially enhanced hypotensive effect Excreted unchanged faeces flux Unknown dialysability fosphenytoin haemodialysis Half-life HD Not dialysed HD Unlikely HDF/High flux Unknown hydrochloride hyperkalaemia hypotensive impairment GFR mL/min Important drug interactions interactions Potentially hazardous itraconazole Litres Half-life liver Metabolism metabolites Molecular weight daltons nephrotoxicity normal renal function normal/ESRF hrs patients undergoing renal Pharmacokinetics Molecular weight plasma possibly increased risk Potentially hazardous interactions Protein binding Rate of administration renal impairment GFR renal replacement therapies replacement therapies APD/CAPD risk of ventricular ritonavir Route Oral Rate severe renal impairment sodium chloride sodium chloride 0.9 Tacrolimus therapies APD/CAPD Unlikely toxicity unchanged in urine Unchanged Metabolism undergoing renal replacement urine ventricular arrhythmias Volume of distribution