Yersinia pestis: Retrospective and Perspective

Ruifu Yang, Andrey Anisimov
Springer, 8 . 2016 . - : 391

This book addresses nearly every aspect of Y. pestis, approaching it from a new perspective. Topics covered include the history, epidemiology, physiology, ecology, genome, evolution, pathogenesis, host-pathogen interaction, big-data-driven research, vaccines, clinical aspects and future research trends. For centuries, scientists have sought to determine where Y. pestis, the most well-known bacterium and one that has caused a number of high-mortality epidemics throughout human history, comes from, what it is and how it causes the disease. This book works to answer these questions with the help of cutting-edge research results. It not only describes the history of plagues, but also stresses plagues effects on human civilization and explores the interaction of Y. pestis with hosts, vectors and the environment to reveal the evolution and pathogenesis. The book offers a valuable guide for researchers and graduate students studying Y. pestis, and will also benefit researchers from other fields, such as infectious diseases, other pathogens and system biology, sharing key insights into bacterial pathogen studies.

 

 - 

.

Plague ADisease Which Changed thePath ofHuman Civilization
1
Discovery ofthePlague Pathogen Lessons Learned
27
Taxonomy ofYersinia pestis
35
Physiology ofYersinia pestis
79
Ecology ofYersinia pestis andtheEpidemiology ofPlague
100
Genome andEvolution ofYersinia pestis
171
Pathology andPathogenesis ofYersinia pestis
193
Genetic Regulation ofYersinia pestis
223
Yersinia pestis intheAge ofBig Data
257
Immunology ofYersinia pestis Infection
273
Plague Clinics Diagnosis andTreatment
293
Plague Vaccines Status andFuture
313
Bacteriophages ofYersinia pestis
361
Perspectives onYersinia pestis AModel forStudying Zoonotic Pathogens
377

-

 (2016)

Dr. Ruifu Yang is a professor at the Beijing Institute of Microbiology and Epidemiology and the Chief-Scientist for National Basic Research Program (973 Program). He serves as the vice president for the Chinese Society for Microbiology. His research focuses on bacterial pathogenesis using genomics- and proteomics-based techniques. He has published more than 100 articles on international well-known journals, such as Nature Genetics, PNAS, BMC Microbiology. Dr. Andrey Anisimov is a professor and deputy director at State Research Center for Applied Microbiology and Biotechnology, Russia.