Lateral DNA Transfer: Mechanisms and Consequences

Лицевая обложка
CSHL Press, 2002 - Всего страниц: 448
This book is about mobile genes—the transfer of DNA between unrelated cells. It discusses the machinery of gene transfer and its wide-ranging biological and health consequences. Mobile DNA makes possible the development of antibiotic resistance in microbes, the conversion of harmless to pathogenic bacteria, and the triggering of cancerous growth in cells. It also contributes to human evolution. This well-illustrated volume contains an up-to-date account of a topic now seen as increasingly important, and will be invaluable for both working scientists and as a textbook for advanced courses.
 

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Содержание

Conjugation Transposition
28
TYPES AND ORIGIN OF ANTIBIOTICRESISTANCE
35
MICROBIAL ECOLOGY AND ANTIBIOTIC RESISTANCE
66
PHAGE TRANSDUCTION AND BACTERIAL PATHOGENESIS
73
Specialized Transduction
103
Scarlet Fever Toxic Shocklike Syndrome and Streptococcus
111
A Pathogenicity Island
117
References
123
Transmission of HIV
216
Control of the HIV Life Cycle
223
Reversing Evasion by Integration
232
GENES FLOATING ON A SEA OF RETROTRANSPOSONS
239
LTR Retrotransposons
245
Mobile Introns
255
Processed Pseudogenes SINEs and Retrogenes
265
MARINERS
273

MICROBIAL GENOMES AND DNA EXCHANGE
129
H7 Sequence
138
Gene Transfer between Bacteria in the Environment
146
Can Microbial Organisms Be Divided into Species?
153
References
161
GENE TRANSFER BY RETROVIRUSES
169
Retroviral Phylogeny
177
Retroviral Integration
185
Retroviral Transduction and Cancer
194
Gene Inactivation by Retroviral Integration
201
References
209
Pelement Transposition
283
The foldback Family
292
References
299
FLUIDITY
303
A TRANSPOSON PROGENITOR OF THE VERTEBRATE IMMUNE
339
DNA TRANSFER AMONG THE DOMAINS OF LIFE
365
CONTROLLING MOBILE ELEMENT ACTIVITY
387
THEMES AND EVOLUTIONARY
417
Index
437
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