D-amino Acids: A New Frontier in Amino Acids and Protein Research : Practical Methods and ProtocolsRyuichi Konno Nova Biomedical Books, 2007 - Всего страниц: 629 D-amino acids have been considered as unnatural amino acids and it has been the common belief that D-amino acids are not present in eukaryotes. However, improvements and developments of analytic methods have shown the D-amino acids are present in a considerable amount of eukaryotes and even in humans. Some of them have been shown to have physiological functions. In this book, all aspects of D-amino acid research are described: analytic methods for D-amino acids, the presence of various D-amino acids in a wide variety of organisms, nutritional aspects of D-amino acids, anabolic and catabolic enzymes for D-amino acids, physiological significance of D-amino acids, pathology of D-amino acids, industrial aspect of D-amino acids etc. |
Содержание
1 CHROMATOGRAPHIC DETERMINATION | 17 |
2 DETERMINATION OF ACIDIC DAMINO ACIDS AND THEIR NMETHYL | 25 |
3 PURIFICATION AND DETERMINATION | 33 |
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2007 Nova Science acetate acetonitrile activity alanine racemase amino acid enantiomers amino acids analysis antibody aspartate aspartic acid assay astrocytes bacterial Biochem biological Biophys buffer cells centrifuged chemical chiral chiral column Chromatogr complex concentration concerning this article containing culture cyclodextrin D-aa D-Ala D-alanine D-amino acid oxidase D-Asp D-aspartate oxidase D-aspartic acid D-Glu D-glutamate D-Phe D-serine D-Trp D'Aniello DAAO DAPA derivatization detection determination eluted enantiomeric enantiomers endogenous enzyme Figure fluorescence free amino acid gene gland glutamate glycine HPLC hydrolysis incubated injection Japan L-Asp liquid chromatography mammalian metabolism methanol method mice molecular mutant NaCl Natl Acad Sci neurons NMDA Nova Science Publishers peak peptide phosphate plasma Proc Natl Acad protein purified racemization rat brain reaction mixture reagent receptor RgDAAO room temperature Ryuichi Konno sample separation sequence serine racemase serum sodium sodium pyrophosphate solution specific standard structure substrate supernatant tissues

